QLT initiate Phase I trial of retinoid QLT091001

QLT has initiated a Phase I safety retinoid QLT091001, that has potential in the treatment of Leber’s Congenital Amaurosis (LCA)

Zydus publish series of PPAR alpha agonists

Zydus have published a series of glycine and oximinobutyric acid PPARα agonists

Cytochroma initiate Phase II trial of Vitamin D analog CTA018 in Chronic kidney disease

Cytochroma have initiated a Phase II clinical trial of Vitamin D analog CTA018 for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD).

Galderma and Shionogi Launch Differin gel for acne vulgaris

Galderma  and Shionogi  have scheduled their launch Differin® Gel 0.1% (Adapalen) for acne vulgaris on October 21, 2008.

Ostarine (MK-2866) meets primary endpoint in Phase II Cancer Cachexia Trial

GTx  have announced Phase II results of SARM Ostarine (MK-2866) in patients with cancer cachexia. The study met its primary endpoint of absolute change in total lean body mass (muscle) compared to placebo.

Basileas Toctino approved in Germany for eczema (atopic dermatitis)

Basilea Pharmaceutica have announced that Toctino (alitretinoin) has been approved by the German health authority “Bundesinstitut für Arzneimittel und Medizinprodukte” for the treatment of eczema (atopic dermatitis)

Dara Biosciences completes Tox studies for PPAR-delta/gamma agonist, DB959

DARA BioSciences has completed all toxicology studies necessary for entering Phase 1 clinical trials for its PPAR-delta/gamma agonist, DB959.

GSK publish series of PPAR α/γ dual activators

GSK have published a series of equipotent PPAR α/γ dual activators

Dong-A publish series of PPAR alpha/gamma dual agonists

Dong-A have published a series of diaryl α-ethoxy propanoic acid PPAR alpha/gamma dual agonists

FDA/Indevus agree on path forward for Nebido

Indevus Pharmaceuticals has reached agreement with the FDA in regard to additional data and risk management required to allow re-submission  of its NDA for its testosterone product Nebido in the treatment of hypogonadism